Marijuana-Like Compound Found Effective Against Late Stage HIV Infection


Marijuana-Like Compound Found Effective Against Late Stage HIV Infection

According to a new study published in the journal PloS ONE, researchers from Mount Sinai School of Medicine discovered that marijuana-like compounds can inhibit the multiplication of human immunodeficiency virus (HIV) in late-stage AIDS by acting on viral receptors.

Medical marijuana is prescribed in diseases which are accompanied by appetite suppression or by sever weight loss also for management of chronic pain, symptoms that are usually present in late stages of AIDS. Through this study, scientists found out that on the surface of immune cells a type of receptors called cannabinoid receptors, CB1 and CB2, are triggered by marijuana-like compounds and can inhibit the dissemination of human immunodeficiency virus throughout the body. It is very important for scientists to understand what are the effects of activated CB1 and CB2 receptors, because in the future they hope to be able to develop new drugs that can slow the progression of HIV infection to AIDS.

“We knew that cannabinoid drugs like marijuana can have a therapeutic effect in AIDS patients, but did not understand how they influence the spread of the virus itself. We wanted to explore cannabinoid receptors as a target for pharmaceutical interventions that treat the symptoms of late-stage AIDS and prevent further progression of the disease without the undesirable side effects of medical marijuana.”, leader of the study said.

When it enters the body, the HIV virus infects T helper lymphocytes (cells that are expressing CD4 receptor), making them ineffective in fighting infection. In order to disseminate, human immunodeficiency virus needs that inactive T helper lymphocytes to be activated by the immune system. In late-stages of AIDS, in viral genome mutations are produced in order to penetrate inactive T helper lymphocytes, action that is mediated by a signaling receptor called CXCR4. By using marijuana-like chemicals, cannabinoid receptor agonists which are able to activate CB2 receptors, researchers observed that activated CB2 receptor can block CXCR4 receptor, thus suppressing the spread of viral infection to inactive T helper lymphocytes.

By triggering CB1 receptors it was observed that marijuana-like compounds have the same effects as marijuana, causing unwanted side effects. Scientists want to develop marijuana-like compounds that are only triggering CB2 receptors, because this CB2 agonist reduce the infection of inactive T helper cells.

“Developing a drug that triggers only CB2 as an adjunctive treatment to standard antiviral medication may help alleviate the symptoms of late-stage AIDS and prevent the virus from spreading,” researchers added.

It has been observed that HIV infects inactive T helper lymphocytes by using CXCR4 receptor only in advanced stages of AIDS, so marijuana-like compounds seem to be effective only in advanced stages of the disease.

Due to the fact that the results of this study were very promising in vitro, researchers want to develop a lab mouse model with late-stage of AIDS to test the effectiveness of marijuana-like compounds that are triggering CB2 receptors in vivo.

CONTINUE READING…

When Do You Think They Were Gonna Tell Us?


 Written by: Msgt. Thomas Vance

Kentuckians anxiously awaiting passage of Senate Bill 129 the Gatewood Galbraith Memorial Medical Marijuana Act, were again disappointed by the failure of Senate Judicial Committee Chairman Senator Tom Jensen to bring the bill up for consideration during the 15 march 2012 committee hearing. Senator Jensen although asked, has as of yet failed to communicate to the citizens as to his reasons for not calling up the bill. Some suspect it is for personal reasons and if it is, the Senator should remove himself from the committee.

Given the fact that rescheduling marijuana from schedule I dangerous and having no medical value to schedule II dangerous but having medical value receives a national poll rating of 81% approval, and that the idea of rescheduling has been vetted in 16 states and Congress, it is hard to imagine what legitimate argument Senator Jensen can come up with to justify his obstructionism on this issue. The national poll rating also indicates a majority of Kentucky’s citizens also favor the idea of medical marijuana.

Supporters have been lighting up the phones and internet trying to convince their legislators to quickly pass this bill and not force our sick and disabled citizens to spend another year having to choose between getting the medicine they sorely need and breaking the law or bowing to law and order and suffering unnecessarily for another year. More tragically some of our people, those fighting cancer, might not be around next year when the Assembly convenes. It is thought that there is enough support that were 129 not being held up it just might pass this year. I have yet to hear a science or logic based argument against medical marijuana laws, or even full legalization, that can pass an honest baloney test.

The Federal Government has known since 1974 that marijuana is an effective anti cancer agent. The Medical College of Virginia, at the request of the Government conducted experiments that showed the administration of marijuana’s primary cannabinoid THC, “slowed the growth of lung cancers, breast cancers and a virus-induced leukemia in laboratory mice, and prolonged their lives by as much as 36 percent.” How long is the Government going to wait before it announces a change in marijuana policy as a result of this investigation?

Kentucky has one of the highest cancer rates in the Nation. Kentucky’s legislators armed with the knowledge of marijuana’s anti cancer properties should be stepping over themselves to make this effective medicine available to our sick and disabled citizens. Kentucky’s universities and research facilities should be leading the way in discovering all the secrets of marijuana, it’s active ingredient tetrahydracannabinol and it’s relationship to the human endocannabinoid system.

When will common decency and doing the right thing finally outweigh our irrational ideology driven worship of the policy of prohibition? That answer can only come from our legislators who above everything else are elected to ‘do the right thing’ by the citizens. In this case the right thing is to make available as fast as possible to Kentucky’s citizens, especially those in a life ending fight with cancer, this effective and safe medicine. Kentucky should opt out of Washington’s irrational war on marijuana users and pass Senate bill 129 the Gatewood Galbraith Memorial Medical Marijuana Act.

Redistricting information


Secretary of State
Secretary of State to Certify Candidates on Monday, February 27, 2012

Press Release Date:
Friday, February 24, 2012

Contact Information:
Lynn Sowards Zellen
Director of Communications
Secretary of State Alison Lundergan Grimes
Cell: 502-330-9839
Email: Lynn.Zellen@ky.gov

Today, the Kentucky Supreme Court affirmed the Franklin Circuit Court’s order that state legislative races for the 2012 election cycle shall be conducted pursuant to the boundaries that were in effect immediately prior to the enactment of House Bill 1. The Court reiterated that the filing deadline for candidates for state Senator and state Representative was February 10, 2012.

Consistent with the Supreme Court’s decision and the Franklin Circuit Court’s order, the Secretary of State’s office will certify candidates to the county clerks on Monday, February 27, 2012. 

###

Marijuana legalization backers puzzling over how to keep stoned drivers off the road


DENVER — Angeline Chilton says she can’t drive unless she smokes pot.

The suburban Denver woman says she’d never get behind the wheel right after smoking, but she does use medical marijuana twice a day to ease tremors caused by multiple sclerosis that previously left her homebound.

“I don’t drink and drive, and I don’t smoke and drive,” she said. “But my body is completely saturated with THC.”

Her case underscores a problem that no one’s sure how to solve: How do you tell if someone is too stoned to drive?

States that allow medical marijuana have grappled with determining impairment levels for years. And voters in Colorado and Washington state will decide this fall whether to legalize the drug for recreational use, bringing a new urgency to the issue.

A Denver marijuana advocate says officials are scrambling for limits in part because more drivers acknowledge using the drug.

“The explosion of medical marijuana patients has led to a lot of drivers sticking the (marijuana) card in law enforcement’s face, saying, ‘You can’t do anything to me, I’m legal,’” said Sean McAllister, a lawyer who defends people charged with driving under the influence of marijuana.

It’s not that simple. Driving while impaired by any drug is illegal in all states.

But it highlights the challenges law enforcement officers face using old tools to try to fix a new problem. Most convictions for drugged driving now are based on police observations, followed later by a blood test.

Authorities envision a legal threshold for pot that would be comparable to the blood-alcohol standard used to determine drunken driving.

But unlike alcohol, marijuana stays in the blood long after the high wears off a few hours after use, and there is no quick test to determine someone’s level of impairment — not that scientists haven’t been working on it.

Dr. Marilyn Huestis of the National Institute on Drug Abuse, a government research lab, says that soon there will be a saliva test to detect recent marijuana use.

But government officials say that doesn’t address the question of impairment.

“I’ll be dead — and so will lots of other people — from old age, before we know the impairment levels” for marijuana and other drugs, said White House drug czar Gil Kerlikowske.

Authorities recognize the need for a solution. Marijuana causes dizziness, slowed reaction time and drivers are more likely to drift and swerve while they’re high.

Dr. Bob DuPont, president of the Institute for Behavior and Health, a non-government institute that works to reduce drug abuse, says research proves “the terrible carnage out there on the roads caused by marijuana.”

One recent review of several studies of pot smoking and car accidents suggested that driving after smoking marijuana might almost double the risk of being in a serious or fatal crash.

And a recent nationwide census of fatal traffic accidents showed that while deadly crashes have declined in recent years, the percentage of mortally wounded drivers who later tested positive for drugs rose 18 percent between 2005 and 2011.

CONTINUE READING…

 

If you think this is bad you haven’t seen ANYTHING yet…


 

 

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If you think this is bad you haven’t seen ANYTHING yet…

If there is ONE thing that I have learned from this life it is that you must be able to adapt to CHANGE.

Just when you think your life is settled into what it is going to be until you die, something comes along and blows it right out of the water. And then what? You start over…

You can NEVER depend upon things to be as you would want them to be. It just will not happen.

Even the thriftiest of investors have lost their lot in a matter of minutes and those who never had two cents have come to be millionaires. And that is just the financial side of it.

Birth, realization of impending death, unexpected death, marriage, divorce, loss of parents, loss of children either by death or other situations are but a few of the changes in life that we can depend upon.

The empty nest syndrome sometimes happens not because your children grow up and move away to their own lives, but because they for whatever reason do not like your life anymore and remove themselves from it. That equates to a death. The death of a marriage of not only a spouse, but the marriage that is entwined within the entire family.

Life throws so many curve balls at us that it is impossible to predict just what will happen next. But the ONE thing that you can ALWAYS depend upon is the unexpected.

Change…If you cannot live through change in this life you will never be able to make it.

My favorite self quotation when times are rough is, “if you think this is bad you ain’t seen nothing yet”, which has in my life always turned out to be very accurate …

and my favorite all around quote is “THIS TOO SHALL PASS”…

And for better or worse you can depend on that much to be true – “This too shall pass”, whether it be into another new, better, worse or indifferent phase you WILL pass. That is just life.

Expect the unexpected and be pleasantly surprised when it doesn’t happen…

Be prepared for the worse when it DOES happen…

That is the hard part. Being prepared. You CANNOT be prepared for everything that will happen in your life. It is just not feasible to analyze all the expected and unexpected happenings of your life and be prepared for them physically, emotionally and financially. In fact, most of the time the “changes” that occur do so in a moment’s notice not giving us the warning of what is to happen so as to be able to “prepare” for the change.

Sometimes, a loss can be a gain. Or, otherwise said-turn your lemons into lemonade.

You have to at some point, either sooner or later, face the facts put in front of you, figure out what you “personally” believe in the most, what you can do the best with your aptitude, attitude and abilities and last but definitely not least—your life experiences, and then find a way to turn that into your “quest for life”.

That, I believe, is the key to what our life is supposed to be upon this Earthly planet.

It is intended to be an educational experience in all facets of human life from birth to death and beyond.

If “two heads are better than one” then just think how much information has been acquired from all of the people’s that have lived upon this “god given” planet since it first came into existence.

Yes, we are here for a reason, and yes, most of us will bear many crosses before we pass from this life to the next and yes, I do believe in “the next life” whether it be in a “heavenly home” or another round of “take him to Earth” again.

The best thing that we can do for ourselves in this life is to learn to accept the changes as they happen and to encompass them into our living experiences to move ourselves forward toward our ultimate goal of accomplishment or, “what you believe in the most”, so as to complete the cycle of life for which you were sent here for. Anything less is unacceptable. Giving up is just not an option in life, only in death.

So in order to remain happy, we must learn to suck up our disappointments in this life and apply our life experiences toward a goal of common good for all, including ourselves. You cannot give up your own belief’s to appease another and remain happy. It just does not happen that way. But if you are fighting a war toward a common good, even when the battles are at their roughest, you can remain happy because you are fighting for and working toward a “greater good” for all…

So whenever you are down and out think to yourself, “Damn, if it is this bad now, what the hell else is going to happen”, and “Damn, this too shall pass”, and get on with it.

ShereeKrider

3/18/2012

Mitch McConnell’s Marijuana Comments Prove He’s A Reefer Madness Fool


Mitch McConnell Thinks Marijuana Causes Death
I just read a media report that exemplifies the stupidity that permeates the halls of Washington D.C

.  The Huffington Post has a story out today talking about how Senate Minority Leader Mitch McConnell (R-Ky) told a constituent via letter that he doesn’t support the idea of marijuana legalization because marijuana can lead to death.

There was a copy of the Mitch McConnell letter posted to grasscity.com by the constituent, which stated, “Hi Blades, got a letter back from Mitch McConnell about legalizing marijuana. I’ll let the letter speak for itself. WOWZA.”  Below is the letter:

mitch mcconnell anti-mariuana letter

What an idiot right?  Did Mitch McConnell actually think that this was a sufficient answer?  When are we going to see a reefer madness politician admit the truth – they make more money opposing marijuana legalization than they do supporting it, so they will never support marijuana legalization as long as that’s the case.  While I think that’s almost as ridiculous as the response Mitch McConnell gave, it would be a breathe of fresh air compared to the constantly BS that they always say.

Let’s analyze what Mitch McConnell wrote.  The second paragraph states, “I have serious concerns about proposals to legalize marijuana for medicinal purposes.  First, synthetic tetrahydrocannabinol, the primary ingredient in marijuana, is currently available in pill for for the treatment of HIV wasting syndrome and other illnesses.”

You cant fix stupid

Politicians who are too lazy to educate themselves on the deficiencies of Marinol should be banned from talking about it, because it is a danger to society.  What if people actually believed Marinol was the end all of medical marijuana, and relied solely on it to provide the benefits that raw cannabis provides?  They would be putting themselves in harms way, as Marinol is not the same thing as real marijuana.  Below is stellar information that proves why Marinol is not as good as real marijuana:

Introduction

Marinol1 (dronabinol) is the only US FDA-approved synthetic cannabinoid. It is often marketed as a legal pharmaceutical alternative to natural cannabis.

Marinol is manufactured as a gelatin capsule containing synthetic delta-9-tetrahydrocannabinol (THC) in sesame oil. It is taken orally and is available in 2.5mg, 5mg and/or 10mg dosages. Marinol may be prescribed for the treatment of cachexia (weight loss) in patients with AIDS and for the treatment of nausea and vomiting associated with cancer chemotherapy in patients who have failed to respond adequately to conventional antiemetic treatments.

Despite FDA approval2, Marinol typically provides only limited relief to select patients, particularly when compared to natural cannabis and its cannabinoids. Marinol should remain a legal option for patients and physicians; however, federal and state laws should be amended to allow for those patients who are unresponsive to synthetic THC the ability to use natural cannabis and its cannabinoids as a medical therapy without fear of arrest and/or criminal prosecution. By prohibiting the possession and use of natural cannabis and its cannabinoids, patients are unnecessarily restricted to use a synthetic substitute that lacks much of the therapeutic efficacy of natural cannabis.

Marinol Lacks Several of the Therapeutic Compounds Available in Natural Cannabis

CONTINUE READING…

Marijuana Smuggler Who Served 30 Years in Prison Wants to Convince Florida Old Folks to Support Medical Marijuana


 

damn-right-old-guy-in-a-wheelc

 

Lucy Steigerwald | March 16, 2012

Robert Platshorn is against the war on drugs; so much so that he spent 5k on two pro-pot billboards. The 69-year-old director of Florida National Organization for the Reform of Marijuana Laws (NORML) did so as part of "The Silver Tour," which is a campaign to convince senior citizens in South Florida that medical marijuana is a good thing.

Platshorn is a rare senior citizen indeed. Seniors (Florida has lots of ’em!) are credited as the reason for the failure of California’s Proposition 19, the marijuana legalization initiative. And in in general, older populations do frown on legalization. Gallup in 2011 charted 39 percent of folks 65 and older as in support of legalization of marijuana; compare that to the 62 percent support from those aged 18-29. The thing about Platshorn, though, is that he spent much of his time in those younger, more pro-pot demographics in prison. In 2008, Platshorn finished out a 30-year term for marijuana smuggling as part of the "Black Tuna Gang."

As part of the Silver Tour, Platshorn put up two billboards in support of medical marijuana, one of which is to the right. They will run for a month.

According to the South Florida Sun-Sentinel:

Down the road apiece, just after a billboard advertising a service for clogged drains, stands the second big sign. "Reschedule Medical Marijuana" it reads. Below it is a quote from former administrative Judge Francis L. Young’s ruling about pot in a 1988 case: "One of the Safest Therapeutically Active Substances Known to Man."

The billboards urge viewers — some 54,500 cars pass that section of Sample Road daily, according to the state Department of Transportation — to learn more at The Silver Tour, the billboards’ sponsor.

Platshorn surely is not the most sympathetic face of the pro-legalization movement, at least not to those on the fence about the issue, but it’s cool that he’s now taking the slow and sneaky path to convince those most skeptical.

Here’s a sampling of a Miami Herald article written on the occasion of the former drug-smuggler’s release from jail. The implication seems to be that weed trafficking was a gentleman’s game in the 1970s. He was, after all, non-violent:

This was just business, and good business wasn’t violent, not in the mid-Seventies, when Platshorn ran his transcontinental racket. Marijuana suppliers were family-run enterprises mediated by political figures and local law enforcement intent on keeping a lid on the trade while lining their own pockets. And he trusted his partners. They were his stoner buddies, and he knew they’d come through for him.

"It was a hippie era," Plat­shorn says. "You tell a guy you’ll pay him $1 million, you pay him."

Those were the years before the cocaine blizzard swallowed South Florida, and Platshorn was just an entrepreneurial pothead leading the 007 existence he’d always dreamed of — and smoking some really good weed while he was at it.

Back in Florida, he had a handful of yachts at his disposal. From a posh suite at theFontainebleau Hotel in Miami Beach, he operated an auto auction, a marina club, and a barbershop. He used canal-front stash houses and wore stylish plaid leisure suits with broad collars as sharp as spearheads….

Platshorn and friends would be accused of smuggling, or at least attempting to smuggle, 500 tons of marijuana into the United States during the mid- to late Seventies. When the gang was busted in September 1978, the DEA proclaimed it the most sophisticated drug ring it had ever encountered.

Platshorn’s 1980 conviction was a major coup for drug enforcement agencies, the first join FBI/DEA enterprise. In all, eight of the gang’s central members were convicted in two federal trials, but the leaders — Platshorn and Robert Meinster — would pay the stiffest price: prison sentences totaling 108 years between them.

The rest here.

Reason on drug policy and marijuana

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CONTINUE READING…

A senior writer at the pot-smoker’s periodical is accused of involvement in one of New York’s biggest marijuana rings.


Behind the Latest Bust at ‘High Times Magazine

Mar 17, 2012 6:19 PM EDT

Tony Dokoupil on the magazine’s history of run-ins with the law.

For almost forty years, High Times magazine has been the premier advocacy rag for marijuana, serving the passionate smoker much as Fox News and MSNBC serve the partisan political junkie. But in their effort to push out “the word of marijuana … the word of legalization … the word of growing,” as managing editor Natasha Lewin has put it, magazine staffers (and one can confidently say readers too) have inevitably pushed up against the law. Some are not just blowing smoke, but smuggling and dealing it too. Sometimes by the ton.

The latest alleged High Times trafficker is Matthew Woodstock Stang, known as “Magazine Guy” in the marijuana underworld. By day he’s employed as an advertising executive and senior writer for the magazine; by night, according to the Manhattan district attorney’s office, he’s a wholesaler in one of the city’s largest and longest-running marijuana rings.

This week his alleged partner, hip-hop magnate Kareem “Biggs” Burke, pleaded guilty to the reduced charge of conspiracy to distribute some 200 pounds of marijuana. Stang, meanwhile, still faces the much more serious charge of wholesaling multiton loads of pot, most of it grown indoors near Miami and trucked to a New York kingpin. If convicted, he faces 10 years to life in prison. As one federal agent said when Stang was first arrested in 2010, it’s “a case of art imitating real life.”

It’s also a case of history repeating itself. High Times was founded by a smuggler named Gary Goodson, a.k.a. Tom King Forcade, who over the years he has been described by his magazine as an “ace in the dope air force” and a “drug-culture mastermind.” He was certainly the latter. Within two years of High Times debuting in 1974—complete with centerfolds of flowering marijuana plants and prices for every kind of pot on the market—Forcade had as many as four million readers a month.

His smuggling, however, was woefully inept. In 1976 he secured a nine-ton load of marijuana that a friend had smuggled into Florida’s Everglades. But he neglected to hire help, which resulted in him taking 24 hours to load the bales into his Winnebago, which was then spotted by a wildlife officer. Police soon blocked the only road to Miami, forcing Forcade to jerk the camper into the swamp. He emerged undiscovered but mosquito-mauled three days later, determined to liquidate High Times—presumably to cover his loses.

Talked out of doing so by friends, Forcade returned to smuggling in 1978. The job called for a pilot to fly to Colombia, pick up a marijuana load, and kick it out over a remote location in southern Florida. Everything worked perfectly until Forcade, who was guiding the first plane to the drop point, radioed instructions for the pilot to “Get lower! Get lower!” The pilot got lower, hit a tree, and died. The gang lost its load.

CONTINUE READING…

Wisconsin patients go West for medical marijuana approvals Continue reading on Examiner.com Wisconsin patients go West for medical marijuana approvals


MADISON – Oregon’s largest newspaper, the Oregonian, published an article on Feb. 20, 2012, that reported on the increasing number of out of state patients registering for Oregon’s medical marijuana program, the only state medical cannabis program that accepts out-of-staters, "Hundreds of out-of-staters find comfort in obtaining Oregon medical marijuana cards."

I was interviewed for the article, which included a photo of me in my apartment posing next to a highway map of Oregon mounted on a door with a copy of my Oregon registration above.

The article included some quotes that really cut to the root of why I would travel to another state each year to gain that state’s approval as a medical cannabis patient:

"Storck, the medical marijuana activist in Wisconsin, which doesn’t have a medical marijuana program, carries his Oregon card with him wherever he goes even though it isn’t likely to offer him much legal protection.

"To be able to have at least one state say, ‘Yes, we accept that you are a patient,’ means so much to me," he said. "It was worth the trip to be recognized as a patient. I have been fighting my whole entire adult life for my medicine. My own home state, where I was born, won’t recognize that."

A map of Oregon hangs in his home, a reminder that his marijuana use is legal here.

"I am really thankful to Oregon," Storck said. "I am legal in every inch of that state and that is a beautiful thought for me." — "Hundreds of out-of-staters find comfort in obtaining Oregon medical marijuana cards," Oregonian, Monday, Feb. 20, 2012.

Continue reading on Examiner.com Wisconsin patients go West for medical marijuana approvals – Madison norml | Examiner.com http://www.examiner.com/norml-in-madison/wisconsin-patients-go-west-for-medical-marijuana-approvals?CID=obinsite#ixzz1pQowwjyx

Marijuana: Willie Nelson endorses Oregon Cannabis Tax Act


Country music star and marijuana enthusiast Willie Nelson is endorsing the Oregon Cannabis Tax Act of 2012. The superstar appears in a recently released ad throwing his support behind the initiative to end the prohibition on marijuana and restore the production of hemp in Oregon.


The Oregon Cannabis Tax Act 2012 is a citizen’s initiative campaign to regulate marijuana and restore hemp. Just as ending alcohol prohibition and regulating that market has protected society, regulating marijuana will help wipe out crime. Restoring hemp, made from the seeds and stems of the marijuana plant for fuel, fiber and food, will put Oregon on the cutting edge of exciting new sustainable green industries and create untold multitudes of new jobs.

Advertisement

The Oregon Cannabis Tax Act 2012 (OCTA 2012) is gathering signatures to qualify for the November general election ballot. If passed, the legislation would:

  • Regulate the legal sale of marijuana to adults through state-licensed stores
  • Allow adults to grow their own marijuana.
  • License Oregon farmers to grow marijuana for state-licensed stores.
  • Allow unlicensed Oregon farmers to grow cannabis hemp for fuel, fiber and food.
  • Raise an estimated $140 million a year by taxing commercial cannabis sales to adults 21 years of age.
  • Save an estimated $61.5 million as law enforcement, corrections and judicial costs.
  • Increase public safety.
  • Restore respect for the law.
  • Create environmentally sustainable jobs.


The following is the text of the OCTA 2012 advertisement by Willie Nelson:


“Hi, I’m Willie Nelson. I urge you to support the Oregon Cannabis Tax Act to regulate marijuana and restore industrial hemp. This initiative will end adult marijuana prohibition and let our criminal justice officers focus limited resources on real criminals, not on marijuana users like me. OCTA will also allow farmers to grow hemp for fuel, fiber & food, to create jobs and help our economy. Please support OCTA. Thank you!”

By all accounts, the prohibition on marijuana is a failure. Marijuana prohibition does not work: prohibition is a historical and contemporary failure. It is time to legalize, tax and regulate marijuana for medical and recreational purposes. It is time to free the weed.

For more information about OCTA 2012, visit the website, sign a petition, make a difference.

For more political news, information, and humor, check out Left Coast Lucy on Facebook.

Continue reading on Examiner.com Marijuana: Willie Nelson endorses Oregon Cannabis Tax Act – Portland Progressive | Examiner.com http://www.examiner.com/progressive-in-portland/marijuana-willie-nelson-endorses-oregon-cannabis-tax-act#ixzz1pQo8nmGH

We are ANTI-PROHIBITIONISTS! We are "Constitutionalists"! We are "Overgrowing the Government"

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